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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human AKT3 overexpression HEK293T cell line is a stable cell line designed to express AKT3, a serine/threonine kinase activated by growth factors such as insulin, IGF1, and PDGF. AKT3 regulates cell survival, growth, glycogen synthesis, and glucose uptake, and contributes to tumorigenesis. This engineered system supports studies of cancer biology, insulin signaling, and neuronal development. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:2~1:4 |
| Cell Line | HEK293T |
| Lineage | Embryonic kidney |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | DMEM & FBS & Penicillin/Streptomycin |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | AKT3 |
| Full Name | Akt Serine/Threonine Kinase 3 |
| Alternative Name | MPPH; PKBG; MPPH2; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma |
| Location | 1q43-q44 |
| Gene ID | 10000 |
| Summary | This AKT family kinase responds to PDGF, insulin, and IGF1 and regulates growth, survival, glycogen synthesis, glucose uptake, and tumor biology. Several alternative transcripts have been identified. |