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GlycoFlux™ Human ALG6 Overexpression Glycoengineered Cell (CAT#: GLJF-0925-JF194)

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1 M cells/vial*2

Description GlycoFlux™ human ALG6 overexpression glycoengineered cell is a stable cell line engineered to increase ALG6 expression, which catalyzes the first glucose addition during N-glycan precursor assembly. As a glycoengineered model, it is relevant for studying congenital disorders of glycosylation, ER stress responses, and protein maturation.
Product Type Overexpression Cell Lines
Cell Line As requested by the client.
Cell Viability >90%
Sterility Test The sterility test indicated an absence of microbial growth.
Identity Test STR identification
Mycoplasma Test Negative
Virus Test Negative for HIV, HBV and HCV.
Genetic Stability Testing We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation qPCR, Sanger Sequencing
Application Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size 1 M cells/vial*2
Product Format Frozen
Shipping Dry ice
Availability Status Made to order
Handling Notes Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target ALG6
Full Name ALG6 alpha-1,3-glucosyltransferase
Alternative Name CDG1C
Location 1p31.3
Gene ID 29929
Summary Catalyzes the first glucose addition to the lipid-linked oligosaccharide precursor in N-linked glycosylation; a critical early step in this essential protein modification process.
For Research Use Only.
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