GlycoFlux™ Human AVPR1A Overexpression HEK293T Cell Line (CAT#: GLJF-0925-JF501)

Description	GlycoFlux™ human AVPR1A overexpression HEK293T cell line is a stable glycoengineered line that constitutively overexpresses the vasopressin V1A receptor (AVPR1A), a GPCR coupling to the phosphatidylinositol-Ca2+ pathway. It enables glycoform-resolved analyses of receptor maturation and surface trafficking, endocytosis/recycling kinetics, and biased-agonism pharmacology as a function of N-glycosylation state.
Product Type	Overexpression Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293T
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	qPCR, Sanger Sequencing
Culture Medium	DMEM & FBS & Penicillin/Streptomycin
Application	Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	AVPR1A
Full Name	Arginine Vasopressin Receptor 1A
Alternative Name	V1aR; AVPR1; AVPR V1a
Location	12q14.2
Gene ID	552
Summary	The vasopressin receptor AVPR1A is part of the GPCR family and stimulates a phosphatidylinositol-calcium second messenger system. It mediates cell contraction, platelet aggregation, and glycogenolysis.