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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human B4GALT3 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses B4GALT3, a β1,4-galactosyltransferase that contributes to LacNAc extension on N-/O-glycans. By increasing galactose capping and poly-LacNAc density, this model enables galectin-lattice tuning, adhesion/trafficking studies, and control of glycoform heterogeneity in recombinant products. |
| Product Type | Overexpression Cell Lines |
| Cell Line | As requested by the client. |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | B4GALT3 |
| Compounds Targeting | N-acetyl-D-glucosamine |
| Full Name | Beta-1,4-galactosyltransferase 3 |
| Alternative Name | beta4Gal-T3 |
| Location | 1q23.3 |
| Gene ID | 8703 |
| Summary | One of a family of enzymes that shape the landscape of glycans, this protein orchestrates the precise addition of galactose to specific sugar molecules, influencing diverse biological functions. |