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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human FUT2 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses FUT2, the secretor α1,2-fucosyltransferase that generates type-1 H antigen in mucosal/secreted glycoconjugates. This model supports microbiome-host interaction studies, mucin glycosylation engineering, and infection models where secretor status modulates pathogen attachment, while enabling quantitative exploration of soluble H-antigen biosynthesis. |
| Product Type | Overexpression Cell Lines |
| Cell Line | As requested by the client. |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | FUT2 |
| Full Name | Fucosyltransferase 2 |
| Alternative Name | Se2; sej; SEC2; SE |
| Location | 19q13.33 |
| Gene ID | 2524 |
| Summary | Encodes one of two galactoside 2-L-fucosyltransferases; crucial for the final step in soluble ABO blood group antigen synthesis. |