GlycoFlux™ Human GALNT12 Overexpression Glycoengineered Cell (CAT#: GLJF-0925-JF240)

Description	GlycoFlux™ human GALNT12 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses GALNT12, initiating O-GalNAc transfer to Ser/Thr residues on target polypeptides. This model supports mucin-domain remodeling, discovery of sequence rules governing Tn/core-1 initiation, and evaluation of how early O-glycosylation alters secretion and receptor activation.
Product Type	Overexpression Cell Lines
Cell Line	As requested by the client.

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	qPCR, Sanger Sequencing
Application	Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	GALNT12
Full Name	Polypeptide N-acetylgalactosaminyltransferase 12
Alternative Name	GalNAc-T12
Location	9q22.33
Gene ID	79695
Summary	Catalyzes the initial step in O-linked protein glycosylation by transferring N-acetylgalactosamine (GalNAc) from UDP-GalNAc to serine or threonine residues on polypeptide acceptors.