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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human GALNT17 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses GALNT17, an O-GalNAc transferase that expands the initiation repertoire of mucin-type O-glycans. It enables comparative initiation mapping across the GALNT family, rational tuning of glycan density on flexible linkers or mucin spacers, and control of cell-surface presentation for targeting or half-life engineering. |
| Product Type | Overexpression Cell Lines |
| Cell Line | As requested by the client. |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | GALNT17 |
| Full Name | Polypeptide N-acetylgalactosaminyltransferase 17 |
| Alternative Name | GALNTL3; GalNAc-T19; GalNAc-T5L; WBSCR17; GalNAc-T17; ppGalNAc-T17 |
| Location | 7q11.22 |
| Gene ID | 64409 |
| Summary | Encodes an N-acetylgalactosaminyltransferase; located near the common deleted region in Williams-Beuren syndrome (WBS), a developmental disorder. |