GlycoFlux™ Human GXYLT2 Overexpression Glycoengineered Cell (CAT#: GLJF-0925-JF234)

Description	GlycoFlux™ human GXYLT2 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses GXYLT2, a glycosyltransferase that elongates O-glucose on EGF repeats (e.g., Notch) with an additional xylose. Augmented EGF-repeat O-glucose extension modulates receptor folding and signaling, enabling structure-function analysis of Notch pathway components and discovery of modulators of EGF-repeat glycan editing.
Product Type	Overexpression Cell Lines
Cell Line	As requested by the client.

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	qPCR, Sanger Sequencing
Application	Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	GXYLT2
Full Name	Glucoside xylosyltransferase 2
Alternative Name	GLT8D4
Location	3p13
Gene ID	727936
Summary	Xylosyltransferase that elongates O-linked glucose bound to epidermal growth factor (EGF) repeats of Notch proteins, influencing their function.