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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human MGAM overexpression HEK293T cell line is a stable glycoengineered line that constitutively overexpresses maltase-glucoamylase (MGAM), a GH31 brush-border enzyme with two catalytic domains. This platform supports secretion/processing assays, N-glycan site-usage mapping, and evaluation of how complex-type capping tunes enzyme stability and activity. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:2~1:4 |
| Cell Line | HEK293T |
| Lineage | Embryonic kidney |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | DMEM & FBS & Penicillin/Streptomycin |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | MGAM |
| Full Name | Maltase-Glucoamylase |
| Alternative Name | MG; MGA |
| Location | 7q34 |
| Gene ID | 8972 |
| Summary | Maltase-glucoamylase, encoded by this gene, participates in the final digestion of starch at the brush border. It shares catalytic similarity with sucrase-isomaltase but is only partially homologous. Both belong to glycosyl hydrolase family 31. |