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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human PPP1R3G overexpression HepG2 cell line is a stable cell line engineered to produce PPP1R3G, a regulatory protein predicted to bind glycogen and PP1, thereby promoting glycogen synthase activity and regulating glucose homeostasis. Localized in the cytoplasm, it participates in fine-tuning glycogen metabolism. This system is suitable for studies on glucose balance, metabolic adaptation, and energy regulation. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:4~1:6 |
| Cell Line | HepG2 |
| Primary Disease | Hepatoblastoma |
| Lineage | Liver |
| Lineage Subtype | Hepatoblastoma |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | DMEM & FBS & Glutamine |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | PPP1R3G |
| Full Name | Protein Phosphatase 1 Regulatory Subunit 3G |
| Location | 6p25.1 |
| Gene ID | 648791 |
| Summary | Predicted to bind glycogen and PP1, regulating glucose homeostasis and glycogen biosynthesis while enhancing glycogen synthase function in the PP1 complex within cytoplasm. |