GlycoFlux™ Human SLC35D1 Overexpression Glycoengineered Cell (CAT#: GLJF-0925-JF161)

Description	GlycoFlux™ human SLC35D1 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses SLC35D1, an ER nucleotide-sugar transporter that imports UDP-glucuronic acid and UDP-GalNAc. Increased luminal substrate supply supports linker tetrasaccharide formation and downstream glycosaminoglycan (GAG) elaboration on proteoglycans. This system is ideal for engineering ECM/GAG content, studying cartilage/matrix biology, optimizing proteoglycan-decorated biotherapeutics, and assessing transporter-dependent bottlenecks.
Product Type	Overexpression Cell Lines
Cell Line	As requested by the client.

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	qPCR, Sanger Sequencing
Application	Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	SLC35D1
Full Name	Solute carrier family 35 member D1
Alternative Name	KIAA0260; UGTREL7
Location	1p31.3
Gene ID	23169
Summary	Transports UDP-glucuronic acid and UDP-N-acetylgalactosamine from the cytoplasm to the endoplasmic reticulum lumen, essential for glycosylation of cellular glycoconjugates.