GlycoFlux™ Human TRIM7 Overexpression HEK293 Cell Line (CAT#: GLJF-0925-JF487)

Description	GlycoFlux™ human TRIM7 overexpression HEK293 cell line is a stable cell line overexpressing TRIM7, a tripartite motif-containing E3 ubiquitin ligase with RING, B-box, and coiled-coil domains. Localized in both cytoplasm and nucleus, TRIM7 regulates glycogen synthesis initiation and contributes to antiviral defense. This system is suited for studies of ubiquitin-mediated signaling, metabolic pathway regulation, and host-pathogen interactions where glycogen metabolism is disrupted.
Product Type	Overexpression Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	qPCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & DMEM
Application	Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	TRIM7
Full Name	Tripartite Motif Containing 7
Alternative Name	GNIP; RNF90
Location	5q35.3
Gene ID	81786
Summary	The encoded protein is a TRIM family member with RING, B-box types 1 and 2, and a coiled-coil region, found in both nucleus and cytoplasm, potentially involved in glycogen synthesis initiation. Multiple isoforms exist.