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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human TRIM7 overexpression Jurkat cell line is a stable glycoengineered line that constitutively overexpresses TRIM7, a TRIM-family E3 with reported links to glycogen initiation and proteostasis. It enables discovery screens connecting ubiquitin signaling to glycogen handling and glycoprotein maturation under stress. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Suspension-growing |
| Passage Ratio | 1:3~1:5 |
| Cell Line | Jurkat cell line |
| Primary Disease | T-cell acute lymphoblastic leukemia (T-ALL) |
| Lineage | T Lymphocyte |
| Lineage Subtype | T-cell acute lymphoblastic leukemia (T-ALL) |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | FBS & Penicillin/Streptomycin & RPMI |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | TRIM7 |
| Full Name | Tripartite Motif Containing 7 |
| Alternative Name | GNIP; RNF90 |
| Location | 5q35.3 |
| Gene ID | 81786 |
| Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Alternative splicing results in multiple transcript variants. |