Specifications Quality Control Target Information Related Products

Specifications

Description

GlycoFlux™ Lenti-SIGLEC16 Viral Particle provides SIGLEC16, a sialic acid-binding receptor implicated in innate defense activation and IL-6 production. This replication-defective vector enables long-term, stably transduced mammalian cells to evaluate activating pathways, ligand specificity, and cytokine responses; selection or fluorescence sorting can be applied directly.

Product Type

Recombinant Lentivirus

Target

SIGLEC16

Species

Human

Promotor

EF1a

Packaging System

Lentivirus

Packaging Cell

HEK293T

Application

The lentiviral vector is a powerful, HIV-based system used for gene delivery, notable for its ability to transduce both dividing and non-dividing cells (e.g., neurons, stem cells). It permanently integrates the gene into the host genome, ensuring long-term, sustained expression for applications in research and studies related to gene therapy.

Shipping

Shipped on dry ice with temperature held at or below -80°C.

Storage

Store at -80°C to maintain their titer and stability.

Handling Notes

Store products at -80°C, and avoid repeated freeze-thaw cycles to maintain viral titer. For safety, always handle the products in a biological safety cabinet, using appropriate personal protective equipment like lab coats, gloves, and eye protection.

Product Disclaimer

These products are for research use only and not for diagnostic or clinical use. The user assumes full responsibility for all safety protocols and compliance with relevant regulations. While we are committed to quality, Creative Biolabs makes no guarantee as to the performance of these products in a specific application.

Quality Control

Titer Assay

qPCR

Mycoplasma Test

Negative

Sterility

Sterility testing confirmed no microbial contamination.

Transduction Evaluation

On request, Creative Biolabs conducts in vitro or in vivo transduction assays to evaluate lentiviral delivery to target cells and to quantify transgene expression and function.

Insert Identity Confirmation

All lentiviral vectors at Creative Biolabs are verified for correct proviral integration by PCR. In this assay, cells are transduced with serial dilutions of the lentiviral vector, harvested after a few days, and genomic DNA is isolated. A defined region of the expected lentiviral insert is then PCR-amplified to confirm identity.

Target Information

Full Name

Sialic Acid Binding Ig Like Lectin 16

Alternative Name

SIGLECP16; Siglec-P16; Sialic Acid Binding Ig Like Lectin

Location

19q13.33

Gene ID

400709

Summary

This protein is predicted to bind sialic acid and is involved in the positive regulation of defense responses to bacteria and the production of interleukin-6. It is predicted to be located in the membrane and active in the plasma membrane.

GlycoFlux™ AAV1-Human SIGLEC16 Viral Particle (CAT#: GLJF-1025-JF874)
GlycoFlux™ MMLV-Human SIGLEC16 Viral Particle (CAT#: GLJF-1025-JF360)
GlycoFlux™ MSCV-Human SIGLEC16 Viral Particle (CAT#: GLJF-1025-JF617)

GlycoFlux™ Lenti-Human SIGLEC16 Viral Particle