Description

GlycoFlux™ MMLV-SIGLEC15 Viral Particle delivers SIGLEC15, implicated in cytoskeleton organization and osteoclast biology; the ready-to-transduce system supports stable mammalian expression to study bone resorption pathways, receptor complexes, and immunomodulation.

Product Type

Recombinant MMLV Retrovirus

Target

SIGLEC15

Species

Human

Promotor

MMLV 5' LTR promoter

Packaging System

Retrovirus

Packaging Cell

HEK293T

Application

This MMLV vector is a common retroviral vector system that permanently integrates a gene into the host cell's genome, allowing for long-term, sustained expression. It is a popular tool for gene manipulation in dividing cells and for generating iPS cells in biomedical research.

Shipping

Shipped on dry ice with temperature held at or below -80°C.

Storage

Store at -80°C to maintain their titer and stability.

Handling Notes

Store products at -80°C, and avoid repeated freeze-thaw cycles to maintain viral titer. For safety, always handle the products in a biological safety cabinet, using appropriate personal protective equipment like lab coats, gloves, and eye protection.

Product Disclaimer

These products are for research use only and not for diagnostic or clinical use. The user assumes full responsibility for all safety protocols and compliance with relevant regulations. While we are committed to quality, Creative Biolabs makes no guarantee as to the performance of these products in a specific application.

Titer Assay	qPCR
Mycoplasma Test	Negative
Sterility	Sterility testing confirmed no microbial contamination.
Transduction Evaluation	On request, Creative Biolabs conducts in vitro or in vivo transduction assays to evaluate lentiviral delivery to target cells and to quantify transgene expression and function.
Insert Identity Confirmation	Creative Biolabs verifies all retroviral vectors by a PCR-based proviral integration check. In brief, cells are transduced with serial dilutions of the retroviral preparation and, after several days, genomic DNA is extracted. A predefined segment of the expected retroviral insert is then amplified by PCR to confirm correct identity and integration.

Full Name	Sialic Acid Binding Ig Like Lectin 15
Alternative Name	CD33L3; HsT1361; SIGLEC-15; Sialic Acid Binding Ig Like Lectin
Location	18q21.1
Gene ID	284266
Summary	The protein is predicted to regulate actin cytoskeleton organization, bone resorption, and osteoclast development. It is expected to be located in the membrane, forming part of a protein-containing complex, and active in the plasma membrane.

GlycoFlux™ MMLV-Human SIGLEC15 Viral Particle (CAT#: GLJF-1025-JF359)

Specifications

Quality Control

Target Information

Related products