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Human Serpin family e member 1 (SERPINE1) protein (CAT#: GP01-116J)

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500 μg

Product Overview Human Serpin family e member 1 (SERPINE1) protein (NP_000593.1) was expressed in . The biological activity was determined by its binding ability in a functional ELISA.
Biological Activity Determined by its binding ability in a functional ELISA.
Species Human
Predicted MW 43 KDa
Purity >98%, determined by SDS-PAGE and HPLC
Conjugation Unconjugated
Target SERPINE1
Full Name Serpin family e member 1
Gene ID 5054
Uniprot ID P05121
Accession Number NP_000593.1
Background This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Alternate Names PAI; PAI1; PAI-1; PLANH1; SERPINE1; Serpin family e member 1
For Research Use Only.
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