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Size | Qty | Add To Basket |
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500 μg |
Product Overview | Human Serpin family e member 1 (SERPINE1) protein (NP_000593.1) was expressed in . The biological activity was determined by its binding ability in a functional ELISA. |
Biological Activity | Determined by its binding ability in a functional ELISA. |
Species | Human |
Predicted MW | 43 KDa |
Purity | >98%, determined by SDS-PAGE and HPLC |
Conjugation | Unconjugated |
Target | SERPINE1 |
Full Name | Serpin family e member 1 |
Gene ID | 5054 |
Uniprot ID | P05121 |
Accession Number | NP_000593.1 |
Background | This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. |
Alternate Names | PAI; PAI1; PAI-1; PLANH1; SERPINE1; Serpin family e member 1 |