Ionizable lipid OF-02

OF-02 is an ionizable lipid specifically utilized to create lipid nanoparticles (LNPs) for the conveyance of RNA. In controlled murine studies, OF-02 LNPs successfully delivered mRNA encoding for human erythropoietin (EPO), leading to a measurable elevation of EPO concentrations in the bloodstream.

1883431-67-1

3,6-Bis[4-[bis[(9Z,12Z)-2-hydroxyoctadeca-9,12-dienyl]amino]butyl]piperazine-2,5-dione; CID 132594335; SCHEMBL20212555; HY-145795

C₈₄H₁₅₂N₄O₆

1314.16

InChI=1S/C84H152N4O6/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-65-77(89)73-87(74-78(90)66-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2)71-63-61-69-81-83(93)86-82(84(94)85-81)70-62-64-72-88(75-79(91)67-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)76-80(92)68-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4/h21-28,33-40,77-82,89-92H,5-20,29-32,41-76H2,1-4H3,(H,85,94)(H,86,93)/b25-21-,26-22-,27-23-,28-24-,37-33-,38-34-,39-35-,40-36-

UMSCHHWDFWCONK-RGLFHLPNSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.