Lipid 319

Lipid 319 is an ionizable, and biodegradable lipid component engineered for the sophisticated formulation of lipid nanoparticles (LNPs). LNP systems containing Lipid 319 have demonstrated enhanced delivery efficacy and superior biodegradability compared to the industry benchmark, DLin-MC3-DMA. This characteristic is particularly important for therapeutics requiring repeated dosing, as LNP systems incorporating this lipid show rapid excretion, avoiding significant accumulation in vivo.

1351586-50-9

L319; Bis[(Z)-non-2-enyl] 9-[4-(dimethylamino)butanoyloxy]heptadecanedioate; Di((Z)-non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate; SCHEMBL517530; DA-64994

C₄₁H₇₅NO₆

678

MFCD32062849

InChI=1S/C41H75NO6/c1-5-7-9-11-13-21-27-36-46-39(43)32-25-19-15-17-23-30-38(48-41(45)34-29-35-42(3)4)31-24-18-16-20-26-33-40(44)47-37-28-22-14-12-10-8-6-2/h21-22,27-28,38H,5-20,23-26,29-37H2,1-4H3/b27-21-,28-22-

DGNMJYUPWDTKJB-ZDSKVHJSSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.