Description
Phosphatidylinositol 3,5-bisphosphate diC16 (PI(3,5)P2 diC16) is a synthetic, purified dipalmitoyl PI(3,5)P2. Phosphoinositides (PIPns) are small constituents of cell membranes but act as essential signaling molecules. PI(3,5)P2 is produced from PI(3)P via the kinase PIKfyve. PI(3,5)P2 is crucial for the retrograde transport from the lysosomal and late endosomal compartments to the Golgi and is implicated in the breakdown of autophagosomes by various phosphatases.
Synonyms
PI(3,5)P2 diC16; Dipalmitoyl phosphatidylinositol 3,5-bisphosphate; PtdIns(3,5)P2 (16:0/16:0); PI(3,5)P2 C16
InChI
InChI=1S/C41H81O19P3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-41-37(45)39(58-61(47,48)49)36(44)40(38(41)46)59-62(50,51)52/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54)(H2,47,48,49)(H2,50,51,52)/t33-,36?,37-,38-,39-,40+,41?/m1/s1