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A synthetic, short-chain phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) molecule. This analog is designed with shorter fatty acyl chains (diC4) to confer significantly enhanced solubility in aqueous solutions compared to its natural long-chain counterparts. It is widely employed as a biochemical tool for studying the binding affinity and enzymatic activity of proteins that interact with the PI(4,5)P2 headgroup in solution or liposome-based systems.