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PI(3,4)P2 diC16 (Phosphatidylinositol 3,4-bisphosphate diC16) is a laboratory-synthesized, purified version of PI(3,4)P2 that contains two palmitoyl (C16) fatty acyl chains. Phosphoinositides (PIPns) are small in concentration within cell membranes, yet they function as indispensable signaling molecules for a variety of cellular communications.