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Recombinant Bornean orangutan T-cell Surface glycoprotein CD8 alpha chain (22-198 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.
Biological Activity
Measured by its binding ability in a functional ELISA.
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).