Recombinant Bovine coronavirus (strain Mebus) Hemagglutinin-esterase (HE) (19-424 aa) [His-Tag], Yeast (CAT#: GP02-057J)

Product Overview	Recombinant Bovine coronavirus (strain Mebus) Hemagglutinin-esterase (19-424 aa) was expressed in Yeast with a 6xHis-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Source	Yeast
Species	Bovine coronavirus (strain Mebus)
Fragment	19-424 aa
Sequence	FDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSYMDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYSYGRCPTAADINTPDVPICVYDPLPLILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA
Tag	6xHis-tag at the N-terminus
Predicted MW	47.7 kDa
Purity	>95%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	HE
Full Name	Hemagglutinin-esterase
Gene ID	918758
Uniprot ID	P15776
Background	This protein is a structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.
Alternate Names	HE protein; E3 glycoprotein; HE; 2b