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Size | Qty | Add To Basket |
---|---|---|
1 mg | ||
500 μg | ||
100 μg |
Product Overview | Recombinant Dog T-cell surface glycoprotein CD8 alpha chain (22-239 aa) was expressed in E. coli with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP. |
Biological Activity | Determined by its binding ability in a functional ELISA. |
Source | E. coli |
Species | Dog |
Fragment | 22-239 aa |
Sequence | SGPSRFRMTPPKVVGQLHAQVELQCQVLLSTAAPGCSWLYQRNEPAARPVFLMYISQSRAKPAEGLDTKHISGQKKTDSTYSLTLSRFRKEDEGYYFCSVLSNSILYFSPFVPVFLPVKPPTTPAPRPPTRAPTNASKPVSPRGETCRPAAGSAVKTSGLDFACEIYIWAPLAGTCAVLLLSLVITIICNHRNRRRVCKCPRPVVRPGGKPSPSEKYV |
Tag | His-tag or Tag free |
Purity | >90%, determined by SDS-PAGE. |
Conjugation | Unconjugated |
Target | CD8A |
Full Name | T-cell surface glycoprotein CD8 alpha chain |
Uniprot ID | P33706 |
Background | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). |
Alternate Names | T-cell surface glycoprotein CD8 alpha chain |