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| Product Overview | Recombinant Human ATP binding cassette subfamily B member 1 (NP_000918.2) was expressed in Yeast with a His-tag at the N-terminus or Tag-free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP. |
| Source | Yeast |
| Species | Human |
| Tag | His-tag at the N-terminus or Tag-free |
| Purity | >90%, determined by SDS-PAGE. |
| Conjugation | Unconjugated |
| Target | ABCB1 |
| Full Name | ATP binding cassette subfamily B member 1 |
| Gene ID | 5243 |
| Uniprot ID | P08183 |
| Accession Number | NP_000918.2 |
| Background | The protein is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. |
| Alternate Names | CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; p-170 |