Recombinant Human BDNF Protein, Glycoengineered Mannose-5 Pichia pastoris (CAT#: GLJF-0722-JF221)

Product Overview	Recombinant Human BDNF protein (NP_001137277.1) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites.
Source	Glycoengineered Mannose-5 Pichia pastoris
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	BDNF
Full Name	Brain-derived neurotrophic factor
Gene ID	627
Uniprot ID	P23560
Accession Number	NP_001137277.1
Background	This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Alternate Names	Brain-Derived Neurotrophic Factor; Neurotrophin; Abrineurin; ANON2; BULN2