Recombinant Human C1QC Protein, Sia-Increased Human Cell Lines (CAT#: GLJF-0722-JF732)

Product Overview	Recombinant Human C1QC protein (NP_001107573.1) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Source	Sia-Increased Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	C1QC
Full Name	Complement C1q subcomponent subunit C
Gene ID	714
Uniprot ID	P02747
Accession Number	NP_001107573.1
Background	This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
Alternate Names	Complement Component 1, Q Subcomponent, C Chain; Complement Component 1, Q Subcomponent, Gamma Polypeptide; C1QG 3 4 C1Q-C