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Recombinant Human C8B Protein, Sia-Increased Human Cell Lines

CAT#: GLJF-0722-JF746

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Human C8B protein (NP_000057.2) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Source
Sia-Increased Human Cell Lines
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
C8B
Full Name
Complement component C8 beta chain
Gene ID
732
Uniprot ID
P07358
Accession Number
NP_000057.2
Background
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections.
Alternate Names
C8B
For Research Use Only.
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