Recombinant Human CEACAM1 Protein, Glycoengineered Human Cell Lines (CAT#: GLJF-0722-JF438)

Product Overview	Recombinant Human CEACAM1 protein (NP_001020083.1) is produced in Glycoengineered Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
Source	Glycoengineered Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	CEACAM1
Full Name	Carcinoembryonic antigen-related cell adhesion molecule 1
Gene ID	634
Uniprot ID	P13688
Accession Number	NP_001020083.1
Background	This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
Alternate Names	Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein); CD66a Antigen; BGP1; BGP; Biliary Glycoprotein; Antigen CD66; BGP-1; BGPI