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Recombinant Human DCN Protein, Sia-Increased Human Cell Lines

CAT#: GLJF-0722-JF776

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Specifications
Product Overview
Recombinant Human DCN protein (NP_001911.1) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Source
Sia-Increased Human Cell Lines
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
DCN
Full Name
Decorin
Gene ID
Uniprot ID
Accession Number
Background
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.
Alternate Names
CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
For Research Use Only.
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