Recombinant Human DCN Protein, Sia-Increased Human Cell Lines (CAT#: GLJF-0722-JF776)

Product Overview	Recombinant Human DCN protein (NP_001911.1) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Source	Sia-Increased Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	DCN
Full Name	Decorin
Gene ID	1634
Uniprot ID	P07585
Accession Number	NP_001911.1
Background	This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.
Alternate Names	CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B