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Size | Qty | Add To Basket |
---|---|---|
50 μg | ||
250 μg |
Product Overview | Recombinant Human Decorin (DCN) protein (NP_001911) (aa31-359) was expressed in E. coli with a His-Tag. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP. |
Biological Activity | Determined by its binding ability in a functional ELISA. |
Source | E. coli |
Species | Human |
Fragment | aa31-359 |
Tag | His-Tag |
Predicted MW | 38.6 KDa |
Purity | >80%, determined by SDS-PAGE and HPLC |
Conjugation | Unconjugated |
Target | DCN |
Full Name | Decorin |
Gene ID | 1634 |
Uniprot ID | P07585 |
Accession Number | NP_001911 |
Background | This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. |
Alternate Names | CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B; DCN; Decorin |