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Recombinant Human EPOR Protein, Sia-Adjusted Human Cell Line

CAT#: GLJF-0922-JF758

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Human EPOR protein (NP_000112.1) is produced in Sia-Adjusted Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with different sialylation degrees.
Source
Sia-Adjusted Human Cell Lines
Species
Human
Tag
His-Tag, FC-Tag or other Tags as required.
Purity
>90%
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
EPOR
Full Name
Erythropoietin receptor
Gene ID
2057
Uniprot ID
P19235
Accession Number
NP_000112.1
Background
Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
Alternate Names
EPO-R
For Research Use Only.
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