Recombinant Human EPOR Protein, Sia-Increased Human Cell Line

Recombinant Human EPOR protein (NP_000112.1) is produced in Sia-Increased Human Cell Line. This expression system is used for the production of glycoproteins with high sialylation with fucosylation.

Sia-Increased Human Cell Lines

Human

His-Tag, FC-Tag or other Tags as required.

>90%

Regular batch

None

EPOR

Erythropoietin receptor

Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.

EPO-R