Recombinant Human F5 Protein, Sia-Adjusted Human Cell Lines (CAT#: GLJF-0722-JF879)

Product Overview	Recombinant Human F5 protein (NP_000121.2) is produced in Sia-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different sialylation degree.
Source	Sia-Adjusted Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	F5
Full Name	Coagulation factor V
Gene ID	2153
Uniprot ID	P12259
Accession Number	NP_000121.2
Background	This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.
Alternate Names	Coagulation Factor V; Coagulation Factor V (Proaccelerin, Labile Factor); Activated Protein C Cofactor; Coagulation Factor V Jinjiang A2 Domain; Proaccelerin, Labile Factor; Factor V Leiden; RPRGL1; THPH2; PCCF; FVL