To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Recombinant Human GDNF protein (NP_000505.1) is produced in Fuco-Adjusted Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degrees.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy.