Recombinant Human herpesvirus 4 (HHV-4) (strain B95-8) Envelope glycoprotein B (gB) (23-260 aa) [6xHis-SUMO-tag], E. coli

Recombinant Human herpesvirus 4 (HHV-4) (strain B95-8) Envelope glycoprotein B (23-260 aa) was expressed in E. coli with a 6xHis-SUMO-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.

Determined by its binding ability in a functional ELISA.

Human herpesvirus 4 (HHV-4) (strain B95-8)

23-260 aa

QTPEQPAPPATTVQPTATRQQTSFPFRVCELSSHGDLFRFSSDIQCPSFGTRENHTEGLLMVFKDNIIPYSFKVRSYTKIVTNILIYNGWYADSVTNRHEEKFSVDSYETDQMDTIYQCYNAVKMTKDGLTRVYVDRDGVNITVNLKPTGGLANGVRRYASQTELYDAPGWLIWTYRTRTTVNCLITDMMAKSNSPFDFFVTTTGQTVEMSPFYDGKNKETFHERADSFHVRTNYKIV

6xHis-SUMO-tag at the N-terminus

43.3 kDa

>90%, determined by SDS-PAGE.

Unconjugated

gB

Envelope glycoprotein B

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.

Envelope glycoprotein B