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Recombinant Human IL10 protein (NP_000563.1) is produced in Sia-Adjusted Human Cell Line. This expression system is used for the production of glycoproteins and antibodies with different sialylation degrees.
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages.