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Recombinant Mouse Glycoprotein hormone beta 5 (Gphb5) (25-130 aa) [His-Tag], Yeast

CAT#: GP02-056J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Mouse Glycoprotein hormone beta 5 (NP_783575.2) (25-130 aa) was expressed in Yeast with a 6xHis-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Source
Yeast
Species
Mouse
Fragment
25-130 aa
Sequence
SSSGNLHTFVGCAVREFTFMAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAYHRVCTYNETRQVTVKLPNCAPGVDPFYTYPMAVRCDCGACSTATTECETI
Tag
6xHis-tag at the C-terminus
Predicted MW
13.3 kDa
Purity
>95%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
Gphb5
Full Name
Glycoprotein hormone beta 5
Gene ID
217674
Uniprot ID
Q812B2
Accession Number
NP_783575.2
Background
This protein functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
Alternate Names
OG; OGH; Zlut; Zlut1
For Research Use Only.
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