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Recombinant Rabies Virus Glycoprotein (G) [His-Tag], Yeast

CAT#: GP01-060J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Rabies Virus Glycoprotein (G) (aa20-459) was expressed in Yeast with a His-Tag. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
Yeast
Species
Rabies Virus
Fragment
aa20-459
Tag
His-Tag
Predicted MW
51.4 KDa
Purity
>90%, determined by SDS-PAGE and HPLC
Conjugation
Unconjugated
Target Information
Target
G
Full Name
Glycoprotein
Uniprot ID
A3RM22
Background
This protein attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Alternate Names
G; Glycoprotein
For Research Use Only.
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