Recombinant Rabies Virus Glycoprotein (G) [His-Tag], Yeast (CAT#: GP01-060J)

Product Overview	Recombinant Rabies Virus Glycoprotein (G) (aa20-459) was expressed in Yeast with a His-Tag. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	Yeast
Species	Rabies Virus
Fragment	aa20-459
Tag	His-Tag
Predicted MW	51.4 KDa
Purity	>90%, determined by SDS-PAGE and HPLC
Conjugation	Unconjugated

Target	G
Full Name	Glycoprotein
Uniprot ID	A3RM22
Background	This protein attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Alternate Names	G; Glycoprotein