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Recombinant Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (G) (20-459 aa) [Tag free], E. coli

CAT#: GPX04-363J

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Specifications
Product Overview
Recombinant Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (20-459 aa) was expressed in E. coli with a Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
E. coli
Species
Rabies virus (RABV) (strain HEP-Flury)
Fragment
20-459 aa
Sequence
KFPIYTIPDKLGPWSPIDLHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVTDLDPYDKSLHSRVFPGGNCSGITVSSTYCSTNHDYTIWMPENLRLGTSCDIFTHSRGKRASKGDKTCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSDETKWCPPGQLVNLHDFRSDEIEHLVEEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVQTWNEIIPSKGCLRVGERCHPHVNGVFFNGIILGSDGHVLIPEMQSSLLQQHMELLESSVIPLMHPLADPSTVFKDGDEVEDFVEVHLPDVHKQVSGVDLGLPKWGKY
Tag
Tag free
Predicted MW
49.7 kDa
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
G
Full Name
Glycoprotein
Uniprot ID
Background
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p76NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Alternate Names
Glycoprotein
For Research Use Only.
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