Similar to plasma glycoprotein, serum glycoprotein is an important component of total serum protein. Serum glycoprotein profiling research is an important way to identify glycoprotein biomarkers for the diagnosis of human diseases. Based on our extensive experience and first-in-class technology platforms in glycoprotein profiling, Creative Biolabs is pleased to provide a full range of high-quality glycoprotein profiling service to our clients all over the world. We can offer high-quality customized services by adjusting protocols to meet even the most specific requirements.

Background of Serum Glycoprotein

Serum glycoprotein is formed by post-translational glycosylation of proteins, which nearly occupy 50% of total protein in serum. Same to other types of glycoprotein, serum glycoproteins play a critical role in a range of biological processes, such as determining the half-life of protein in the blood, affecting other proteins transportation, changing cellar processes and immunizing, and some signal pathways. Abnormal alteration in both types and concentrations of glycans and glycoproteins in human serum has been demonstrated to be related to an increasing number of human diseases. Similar to plasma glycoproteins, serum glycoproteins have also been reported to function as glycoprotein biomarkers for several diseases particular for cancers.

Serum Glycoprotein Profiling

  • The close association between N- or O-glycans alteration in serum and a variety of different pathological states has not been elucidated clearly yet
  • The serum is an easily available body fluid sample that contains a high concentration of glycoproteins
  • Though some glycoproteins in human serum have been investigated deeply and thoroughly, little is known about the human serum glycoprotein profiles and other mammalian species if necessary

Due to the reasons above, Creative Biolabs has developed cutting-edge technology platforms for serum glycoprotein profiling. With years of experience in glycoprotein profiling, we provide our customers with a comprehensive serum glycoprotein profiling service with the best quality and most competitive price.

Serum glycoproteins research experimental flowchart by combining lectin capture strategies with mass spectrometry approaches Fig.1 Serum glycoproteins research experimental flowchart by combining lectin capture strategies with mass spectrometry approaches (Drake, 2006).

Let’s Work Together to Gain Success on Serum Glycoprotein Profiling

  • Abundant experience and good reputation in serum glycoprotein profiling research
  • A full range of powerful technology platforms based on glycomics for profiling research
  • Ph.D. level scientists and professional teams specialized in glycoprotein profiling research
  • Perfect after-sale service system based on decades of years of industry background

In terms of serum glycoprotein profiling research, Creative Biolabs guarantees that our high-quality services and professional solutions will perfectly promote your success. If you are interested in our serum glycoproteins profiling service, please just feel free to contact us for more information and a detailed quote.

Reference

  1. Drake, R.R.; et al. Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers. Molecular & Cellular Proteomics Mcp. 2006, 5(10):1957-67.

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