To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Sphingosine is attached to the tetramethylrhodamine (TMR) fluorophore, yielding a highly visible fluorescent probe. Sphingosine, a lipid hydrolysis product of ceramide, is recognized as a key second messenger that actively inhibits enzymes like protein kinase C (PKC). The TMR label permits precise, real-time visualization of this bioactive molecule's intracellular trafficking, its movement across membranes, and its phosphorylation into sphingosine 1-phosphate by sphingosine kinases.