Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Histamine receptor H1 |
| Gene Name | HRH1 |
| Uniprot | P35367 (Human); P70174 (Mouse) |
| Synonym | H1R; H1-R; HH1R; hisH1; histamine H1 receptor; histamine receptor, subclass H1 |
| Background | Histamine H1 receptor (H1R or HRH1), is an integral membrane protein which in human is encoded by HRH1 gene. It is recognized as a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors and is predominantly expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous system. This receptor is activated by the biogenic amine histamine. HRH1 is linked to an intracellular G-protein (Gq) that activates phospholipase C and the inositol triphosphate (IP3) signaling pathway. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX183 | NativeExtract™ Human HRH1 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX4065K | MemDX™ Membrane Protein Human HRH1 (Histamine receptor H1) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| MP0526X | MemDX™ Membrane Protein Human HRH1 (Histamine receptor H1) with GST-tag for Antibody Discovery | Wheat germ cell-free | Full length | N/A |
| MP0525X | MemDX™ Membrane Protein Human HRH1 (Histamine receptor H1) without tag for Antibody Discovery | Wheat germ cell-free | Full length | Liposome |
| MPX4642K | MemDX™ Membrane Protein Human HRH1 Expressed in E.coli, Partial (211-416aa) | E.coli | Partial | N/A |
| Please for more products or customization | ||||
L*o: I recently purchased the HRH1 protein from Creative Biolabs, and I couldn't be happier. The customer support was also very responsive and helpful.
22/ Jul/2023
N**k: The documentation provided was comprehensive and very useful. The shipping was fast, and the packaging was excellent, ensuring the product arrived in perfect condition. Great job, Creative Biolabs!
14/ Sep/2023
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers RNAi services. In the context of HRH1 gene therapy, small interfering RNA (siRNA) or small hairpin RNA (shRNA) can be used to knock down HRH1 expression. For example, researchers have transfected cells with siRNA or shRNA targeting HRH1 using electroporation or viral vectors. This approach has been shown to effectively reduce HRH1 expression and modulate cellular functions.
Creative Biolabs offers gene editing services. This method involves designing guide RNAs (gRNAs) that target specific regions of the HRH1 gene. Once the gRNA binds to the target site, it induces double-strand breaks, which can be repaired by non-homologous end joining (NHEJ) or homology-directed repair (HDR).
Creative Biolabs offers gene expression analysis services. To understand the role of HRH1 in various diseases, gene expression analysis can be performed using techniques such as quantitative PCR (qPCR) and RNA sequencing. This helps in identifying the expression levels of HRH1 and its downstream targets in different tissues and conditions.
Creative Biolabs offers comprehensive and innovative services to drive the development of HRH1 cell therapy. Please for more services.
Creative Biolabs offers gene editing services for enhanced cell therapy. Edit the HRH1 gene in immune cells (e.g., T cells or CAR-T cells) to enhance their therapeutic efficacy. For example, knocking out HRH1 in T cells can reduce histamine-mediated suppression of immune responses. This can help in studying the role of HRH1 in stem cell differentiation and tissue regeneration.
Creative Biolabs offers co-culture systems development services. Use co-culture systems to study the interactions between HRH1-expressing cells and other cell types. For example, co-culturing HRH1-expressing neurons with astrocytes can help in understanding the role of HRH1 in neuroinflammation.
Creative Biolabs offers 3D cell culture model development services. Develop 3D cell culture models to mimic the in vivo environment. These models can provide more physiologically relevant insights into HRH1 function and drug responses.
With the world's broadest range of knowledge in membrane proteins, Creative Biolabs applies its expertise in a variety of membrane protein studies to offer a comprehensive solution for membrane protein preparation. Please feel free to for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
