Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | 5-hydroxytryptamine receptor 1F |
| Gene Name | HTR1F |
| Uniprot | P30939 (Human); Q02284 (Mouse) |
| Synonym | 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled; serotonin receptor 1F |
| Background | 5-hydroxytryptamine receptor 1F, also called serotonin receptor 1F, is one of the subtypes for serotonin receptor (5-HT receptor) which in human is encoded by HTR1F gene. It belongs to the G protein-coupled receptor (GPCR) family. HTR1F shares 61% sequence homology with the HTR1E receptor, which is the greatest among all the 5-HT receptors. HTR1Fs are found in spinal cord, mesentery, uterus, and brain, specifically in cortex, nucleus accumbens, striatum, amygdala, and hippocampus. And thus, HTR1F has supposed to be the subject of intense research as a target for anti-migraine drugs. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX348 | NativeExtract™ Human HTR1F Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| S01YF-0622-KX69 | MemDX™ Recombinant Human HTR1F Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MP1359J | MemDX™ Membrane Protein Human HTR1F (5-hydroxytryptamine receptor 1F) for Antibody Discovery | E.coli cell-free | Full length | Detergent |
| Please for more products or customization | ||||
E**a: I recently purchased HTR1F protein from Creative Biolabs, and I’m extremely satisfied with the product quality. The protein was delivered with detailed documentation, including purity analysis and proper storage instructions.
13/ Nov/2023
R***r: Their team kept us updated at every step, and the final product worked flawlessly in our assays.
11/ Feb/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers gene replacement services. In instances where a loss-of-function mutation within the HTR1F locus is implicated in a specific cellular or organismal phenotype, a potential therapeutic strategy involves the introduction of a wild-type allele into the affected target cells. This necessitates the utilization of an appropriate gene delivery vector, perhaps an adeno-associated virus, to facilitate efficient transduction and subsequent transgene expression. Furthermore, the introduced genetic material can undergo meticulous engineering to optimize both its transcriptional and translational efficiency, as well as its overall stability within the cellular milieu.
Creative Biolabs offers gene silencing services. Scenarios wherein the pathological state arises due to the excessive expression of the HTR1F gene or its cognate downstream signaling molecules necessitate alternative therapeutic interventions. In such contexts, the selective abrogation of gene expression can be achieved through the strategic deployment of nucleic acid-based technologies. Specifically, RNA interference (RNAi) and antisense oligonucleotides (ASOs) represent powerful modalities for achieving targeted gene silencing. These molecular tools can be meticulously engineered to exhibit high complementarity to the messenger RNA (mRNA) transcripts of HTR1F. Consequently, upon introduction into the relevant cellular compartment, these agents can effectively impede the translation of the HTR1F mRNA into functional protein.
Creative Biolabs offers comprehensive and innovative services to drive the development of HTR1F cell therapy. Please for more services.
Creative Biolabs offers patch-clamp techniques development services. To elucidate the functional contributions of the 5-hydroxytryptamine receptor 1F to cellular physiology, particularly in the realms of excitability and neurotransmission, the application of patch-clamp electrophysiology to cells expressing this receptor constitutes a powerful investigative approach. Through this methodology, precise measurements of key electrical parameters become feasible. These parameters encompass fluctuations in the plasma membrane potential, the kinetics and frequency of action potential generation, and the characteristics of synaptic currents elicited upon the modulation of HTR1F activity.
Creative Biolabs offers gene expression analysis services. To comprehensively delineate the molecular landscape governed by the 5-hydroxytryptamine receptor 1F, the application of transcriptomic profiling methodologies, such as RNA sequencing (RNA-seq) or quantitative polymerase chain reaction (qPCR), is indispensable for the analysis of gene expression patterns in cells expressing this receptor. These techniques facilitate the identification of downstream effector genes and the intricate signaling pathways modulated by HTR1F activation.
Creative Biolabs offers cell transplantation development and preclinical research services. Following the ex vivo genetic modification of a patient's own cells, a critical step in the therapeutic paradigm involves the reintroduction, or transplantation, of these autologous cells back into the donor organism. This strategy inherently mitigates the potential for adverse immunogenic responses and subsequent graft rejection, a significant advantage in the context of cell-based therapies. Consequently, this approach holds considerable promise for the treatment of a spectrum of pathological conditions.
Creative Biolabs spares no effort to provide a comprehensive solution for membrane protein studies for our worldwide clients. In complement to our regular membrane protein preparation services, we also offer customized services based on the requirements of our clients. Please feel free to for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
