Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | 5-hydroxytryptamine receptor 2B |
| Gene Name | HTR2B |
| Uniprot | P41595 (Human); Q02152 (Mouse) |
| Synonym | 5-HT2B; 5-HT-2B; 5-HT(2B); 5-HT 2B receptor; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B variant b; serotonin receptor 2B |
| Background | 5-hydroxytryptamine receptor 2B (5-HT2B), alternatively called serotonin receptor 2B, is a member of the 5-HT2 receptor for the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). 5-HT2B is encoded by HTR2B gene in human. It has been found in the stomach fundus, intestine, kidney, heart, and lung, as well as in the brain, specifically in the cerebellum, cerebral cortex, amygdala, substantia nigra, caudate, thalamus, hypothalamus, and retina. HTR2B is also expressed in a number of blood vessels. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX346 | NativeExtract™ Human HTR2B Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| S01YF-0622-KX70 | MemDX™ Recombinant Human HTR2B Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MP1360J | MemDX™ Membrane Protein Human HTR2B (5-hydroxytryptamine receptor 2B) for Antibody Discovery | E.coli cell-free | Full length | Detergent |
| MP0533X | MemDX™ Membrane Protein Human HTR2B (5-hydroxytryptamine receptor 2B) with GST-tag for Antibody Discovery | Wheat germ cell-free | Full length | N/A |
| MP0532X | MemDX™ Membrane Protein Human HTR2B (5-hydroxytryptamine receptor 2B) without tag for Antibody Discovery | Wheat germ cell-free | Full length | Liposome |
| Please for more products or customization | ||||
H***l: The HTR2B protein I received from Creative Biolabs was of excellent quality. The documentation provided (COA, MSDS, and sequence verification) was thorough and matched the product specifications.
24/Mar/2024
L**a: Creative Biolabs’ team was responsive and professional throughout the process. They answered my technical questions promptly and provided additional data upon request, which was very helpful for our research.
11/Oct/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers gene overexpression services. The controlled augmentation of HTR2B gene expression within targeted cellular populations or specific tissue architectures is routinely achievable through the application of various viral vector systems. Specifically, adenoviral vectors, lentiviral vectors, and adeno-associated viral (AAV) vectors represent established modalities for this purpose. This precise overexpression strategy affords investigators a robust platform to meticulously dissect the downstream ramifications of elevated HTR2B levels.
Creative Biolabs offers transgenic animal models development services. The generation of transgenic murine models engineered to exhibit elevated HTR2B gene expression offers a crucial avenue for elucidating the gene's multifaceted involvement in both normative physiological processes and various pathological states. These sophisticated biological platforms, consequently, serve as invaluable instruments for the rigorous in vivo assessment of prospective therapeutic strategies specifically designed to modulate HTR2B activity.
Creative Biolabs offers gene therapy delivery systems research services. To deliver components for HTR2B gene therapy, various non-viral delivery platforms warrant thorough investigation. These modalities, which notably include lipid nanoparticles and polymeric nanoparticles, circumvent some of the inherent limitations associated with viral vectors. These non-viral approaches may offer compelling advantages, perhaps exhibiting enhanced safety profiles and streamlining the complexities associated with large-scale production. Thus, their exploration is a critical avenue in the advancement of HTR2B-targeted interventions.
Creative Biolabs offers comprehensive and innovative services to drive the development of HTR2B cell therapy. Please for more services.
Creative Biolabs offers immunohistochemistry services. This technique facilitates the robust detection of HTR2B within a diverse array of biological samples, encompassing various tissues and distinct cellular populations. This methodology, in turn, permits the meticulous mapping of the receptor's native spatial distribution throughout the organism. Such comprehensive mapping efforts are crucial, as they inherently provide foundational insights into the intrinsic biological roles of HTR2B-expressing cells and, critically, their potential significance within the context of therapeutic interventions.
Creative Biolabs offers immune response and safety evaluation services. A critical prerequisite for the advancement of efficacious and secure cellular therapeutics involves the meticulous evaluation of the host immune response provoked by HTR2B-modified cells. This assessment extends to a thorough appraisal of the potential for unintended adverse immunological reactions or, indeed, overt immunogenicity. Such comprehensive immunological profiling is indispensable, as it directly informs the optimization of therapeutic strategies, aiming to mitigate risks and enhance the overall safety profile of these nascent interventions.
Creative Biolabs offers biomarker identification services. The identification of robust biomarkers is paramount for advancing HTR2B cell therapy. Such markers serve a dual purpose: they can prospectively forecast an individual's therapeutic responsiveness and, concurrently, enable the dynamic, real-time monitoring of treatment efficacy. This pursuit of predictive and prognostic indicators encompasses a diverse spectrum of modalities. Uncovering these biomarkers is critical for the development of personalized and precisely monitored therapeutic interventions.
Scientists in Creative Biolabs are devoted to offering value-added services to our clients all over the world, in an attempt to help to achieve their research goals on membrane protein preparation. Please feel free to for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
