Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | 5-hydroxytryptamine receptor 6 |
| Gene Name | HTR6 |
| Uniprot | P50406 (Human); Q9R1C8 (Mouse) |
| Synonym | 5-HT6; 5-HT6R; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; serotonin receptor 6 |
| Background | HTR6, encoded by HTR6 gene, is a member of the seven-transmembrane G protein-coupled receptor family, coupled with the Gs alpha subunit. It is found in the central and peripheral nervous systems, involved in the mediation of excitatory and inhibitory neurotransmission. Now most studies are designed to investigate the characters of HTR6 acting as a potential therapeutic target for neurological disorders, such as Alzheimer's disease. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX342 | NativeExtract™ Human HTR6 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3576K | MemDX™ Membrane Protein Human HTR6 Expressed in vitro E.coli expression system, Full Length of Mature Protein | E.coli cell-free | Full length | Detergent |
| Please for more products or customization | ||||
30/Oct/2023
B*n: Perfect for our lab’s needs! HTR6 protein showed high quality and consistency in Western blot experiments.
12/Aug/2024
We provide tailored solutions to meet your specific requirements. Please inquire us for more services.
Creative Biolabs offers RNA interference services. The intricate process of investigating gene function often necessitates a targeted perturbation of specific genetic elements. To this end, the precise design and subsequent de novo synthesis of small interfering RNA (siRNA) oligonucleotides, meticulously engineered to exhibit specificity for the messenger RNA transcript of the HTR6 gene, is paramount. Following this crucial synthetic step, the efficient intracellular delivery of these synthesized siRNA constructs into the designated cellular milieu can be achieved through the application of appropriate transfection methodologies and reagents. This strategic intervention, fundamentally, aims to elicit a significant reduction, or "knockdown," in the endogenous expression of the HTR6 gene. Thus, this methodological approach offers a robust avenue for unraveling intricate cellular pathways and identifying novel interventions.
Creative Biolabs offers of HTR6 gene polymorphisms research services. Elucidating the intricate interplay between genetic variations and phenotypic outcomes is a critical endeavor in contemporary biomedical research. A comprehensive investigation into the associations between polymorphisms within the HTR6 gene and a spectrum of diverse pathological conditions or differential pharmacological responses is, therefore, warranted. Such rigorous empirical analyses are instrumental; they furnish invaluable insights into the underlying genetic architecture of HTR6-associated pathologies. Ultimately, this foundational knowledge may perhaps pave the way for the development of highly individualized and efficacious therapeutic paradigms, thereby advancing precision medicine.
Creative Biolabs offers comprehensive and innovative services to drive the development of HTR6 cell therapy. Please inquire with us for more services.
Creative Biolabs offers serotonergic stimulation services. The elucidation of cellular responses to specific neurotransmitters often necessitates highly refined investigative methodologies. To comprehensively analyze the effects of serotonin on cellular populations endogenously expressing the HTR6 receptor, the employment of a specialized cilia-targeted serotonin biosensor is demonstrably advantageous. This sophisticated molecular tool permits real-time, localized detection of serotonin activity. Subsequently, the precise release of serotonin onto cellular cilia can be precisely orchestrated through either optogenetic or chemogenetic stimulation of serotonergic axons. Following this targeted neurotransmitter delivery, the subsequent activation dynamics of ciliary HTR6 receptors can be meticulously quantified and rigorously analyzed, perhaps revealing novel insights into receptor pharmacology or cellular signaling pathways.
Creative Biolabs offers electrophysiology services. The intricate mechanisms governing synaptic function and information processing within neuronal circuits are subjects of intense biological inquiry. A compelling research avenue involves the comprehensive investigation into the precise role of the HTR6 receptor in both synaptic plasticity and fundamental neurotransmission processes, a pursuit often facilitated by sophisticated electrophysiological techniques. Crucially, such electrophysiological analyses can precisely delineate the effects of either direct activation or selective pharmacological blockade of HTR6 receptors on these fundamental synaptic phenomena. This systematic approach, therefore, perhaps offers invaluable insights into the physiological contribution of HTR6 to neuronal circuit function and its potential implications for neurological processes.
As a forward-looking research institute as well as a leading custom service provider in the field of membrane protein, Creative Biolabs has won good reputation among our worldwide customers for successfully accomplishing numerous challenging projects including generation of many functional membrane proteins. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
