Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | 5-hydroxytryptamine receptor 7 |
| Gene Name | HTR7 |
| Uniprot | P34969 (Human); P32304 (Mouse) |
| Synonym | 5-HT7; 5-HT-7; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); HTR7 |
| Background | HTR7 belongs to the G protein-coupled serotonin receptor family which has seven transmembrane domains. It is encoded by HTR7 gene and exists three different splice variants with different carboxy terminals. The receptor couples with Gs subunit of cell surface involving in regulating the production of intracellular signaling molecule cAMP and multiple signaling pathway transductions. Recently, a lot of studies indicate that the receptor can be used as a drug development target for the treatment of several clinical disorders, such as neuromodulation disorder, mental disorders. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX341 | NativeExtract™ Human HTR7 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| S01YF-0622-KX71 | MemDX™ Recombinant Human HTR7 Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MP1361J | MemDX™ Membrane Protein Human HTR7 (5-hydroxytryptamine receptor 7) for Antibody Discovery | E.coli cell-free | Full length | Detergent |
| MP0537X | MemDX™ Membrane Protein Human HTR7 (5-hydroxytryptamine receptor 7) with GST-tag for Antibody Discovery | Wheat germ cell-free | Full length | N/A |
| MP0536X | MemDX™ Membrane Protein Human HTR7 (5-hydroxytryptamine receptor 7) without tag for Antibody Discovery | Wheat germ cell-free | Full length | Liposome |
| Please for more products or customization | ||||
G***e: High-quality protein with excellent purity and functionality. Perfect for our experiments.
16/Sep/2023
S*y: Customer service was responsive and helpful. Highly recommended for research use!
22/Jun/2024
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers sequencing and variant Analysis services. The identification of genetic determinants influencing disease susceptibility and therapeutic efficacy constitutes a cornerstone of contemporary biomedical research. To this end, a comprehensive molecular genetic inquiry necessitates the execution of either whole-genome sequencing or highly targeted sequencing of the HTR7 gene and its cognate regulatory elements. This systematic genomic interrogation aims to discern specific genetic variants exhibiting an association with particular disease phenotypes or differential responses to pharmacological interventions. Such precision genomic approaches, therefore, offer the potential to illuminate the genetic underpinnings of complex disorders and perhaps guide the development of more personalized treatment modalities.
Creative Biolabs offers of pharmacogenomics research services. The intricate interplay between genetic predisposition and pharmacological outcomes represents a critical frontier in modern medicine. A robust research imperative, therefore, lies in the comprehensive investigation of associations between specific genetic variants within the HTR7 gene and an individual's differential response to therapeutic interventions. This focused inquiry aims to inform the development of highly personalized therapeutic strategies. Such precise pharmacogenomic findings hold considerable promise; they may perhaps facilitate the stratification of patients for optimal treatment regimens, thereby moving closer to a truly individualized medical practice.
Creative Biolabs offers comprehensive and innovative services to drive the development of HTR7 cell therapy. Please for more services.
Creative Biolabs offers stable cell line development services. The systematic investigation of gene function frequently necessitates the establishment of cellular model systems exhibiting modulated expression of a target gene. Consequently, the development of stable cell lines that either robustly overexpress or demonstrate a sustained knockdown of the HTR7 gene constitutes a pivotal initial step for numerous cellular and molecular inquiries. For instance, the creation of a human HTR7 stable cell line within an HEK293 cellular background provides an invaluable tool; such a validated system can be rigorously employed for detailed functional characterizations of the receptor and for high-throughput pharmacological screening initiatives. Such well-characterized cellular models are, therefore, essential for dissecting the multifaceted biological roles of HTR7 and perhaps identifying novel therapeutic targets.
Creative Biolabs offers knockout and knock-in mice models development services. The advent of advanced genomic manipulation techniques has profoundly transformed the landscape of biomedical research, offering unprecedented capabilities for in vivo functional genomics. Accordingly, the strategic utilization of contemporary gene-editing technologies to engineer genetically modified murine models, specifically those featuring either a complete ablation (knockout) or targeted insertion (knock-in) of the HTR7 gene, represents a powerful investigative approach. These meticulously designed animal models are indispensable for elucidating the multifaceted physiological and pathophysiological roles of HTR7 across a spectrum of complex diseases.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
