Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsAt Creative Biolabs, hundreds of monoclonal antibodies (mAbs)-secreting hybridomas are ready to develop antibodies against a wide range of antigens, including bacteria, viruses, and immunoglobulins. As an expert in the field of hybridoma research, Creative Biolabs ensures that all of our premade or customized cell lines go through a comprehensive quality control and qualification process.
Hybridoma technology is one of the most commonly used methods for the production of mAbs. In this process, the host animal is first immunized with a specific antigen, then antibody-producing B lymphocytes are isolated from the host and fused with an immortal myeloma cell line to form a hybridoma cell line, which combines the characteristics of antibody production and unlimited proliferation. These hybridoma cells are grown in the laboratory to produce mAbs directed against specific antigens. Additionally, favorable hybridoma cell lines can be cryopreserved for durable mAb production. Therefore, hybridomas are considered to be a vital avenue to maintain a convenient and inexhaustible supply of highly pure and specific mAbs.
Fig.1 The production of monoclonal antibodies by hybridoma technology. (Rajewsky, 2019)
Since the hybridoma cells become stable and immortal, these cell lines allow unlimited production of a variety of different mAbs specific to a given antigen. Antigenic molecules include enzymes, hormones, and specific structures of viruses, bacteria, and eukaryotic cells. The mAbs generated by this method are highly sensitive and specific and play a crucial role in diagnosis, imaging, and immunotherapy. In addition, radioactively labeled or fluorescent-labeled mAbs were used as probes for the detection or imaging of tumor antigens in living systems. In conclusion, hybridoma technology is a perfect tool for the research of various fields such as toxicology, pharmacology, medicine, and cell molecular biology.
A variety of hybridoma cells for research are available at Creative Biolabs. These cells are capable of producing immunoglobulins that are specific for viral, bacterial, or cellular targets. Our hybridoma cell lines including but not limited to:
Hundreds of mAbs are generated, and the success rate is over 97%.
We perform multiple types of immunization strategies such as protein, hormones, peptide, and DNA immunization.
With our optimized platforms, our experienced scientists provide you with cost-effective customized solutions for your immunization schedule and hybridoma screening method.
Purified antibodies will be tested and qualified to ensure your project progresses.
Hybridomas are used as the basis for the large-scale production of mAbs for diagnostic or therapeutic applications. Creative Biolabs has many years of experience in the production of hybridoma cells. If you have special requirements for your project, we will work with you to make sure the project complies with your specifications. Please feel free to contact us for more details.
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All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
