6PGDH-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR58
Cell Type: CD4⁺ T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: NMNAT1
RNA types: mRNAs
Modification: m1A
RNA editing: A to I
Short Description
This product is a 6PGDH-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-YTHDF2-ALKBH5-NMNAT1-HEX) modification and Mevalonate pathway-mediated (nELAVL-SAM-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
NMNAT1
RNA types
mRNAs
Modification
m1A
Label
HEX
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m1A-METTL14-YTHDF2-ALKBH5-NMNAT1-HEX
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
HDAC11 overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Colorectal Cancer
RNA-binding proteins
nELAVL
Metabolic Reprogramming
Mevalonate pathway-nELAVL-SAM-ADP
Target
6PGDH
Alternative Names
6PGDH
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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