AccuMetab™ Human SULT1B1 Enzyme, Catalytically Active
CAT#: ITS-0426-YL84
Product Type: Recombinant Phase II Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Human SULT1B1 for high-fidelity Phase II sulfation ADME assays.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Highly abundant in both the human liver and intestine, SULT1B1 is critical for the sulfation of thyroid hormones and specific pharmaceutical compounds. ADME researchers utilize this enzyme to map endocrine drug clearance and identify alternative, non-P450 metabolic pathways.
Key Features
High-concentration E. coli cytosol format (10 mg/mL); Maps alternative non-P450 thyroid/endocrine clearance; Requires PAPS cofactor for rapid assay initiation; Standardized for highly reproducible Phase II profiling
Applications
Phase II Drug Metabolism, Conjugation Studies
Research Areas
ADME; Phase II Conjugation
Species
Human
Expression System
Recombinant enzymes are prepared from E. coli cytosolic protein expressions.
Physical Form
Liquid
Size
1 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.